Why Does Semaglutide Require Proper Storage?
Semaglutide belongs to a class of medications called GLP-1 receptor agonists. These are delicate protein-based drugs that can degrade if not stored under optimal conditions.
When exposed to temperatures outside the recommended range, the medication may lose its stability, rendering it less effective or even harmful.
Proper storage ensures the medication remains potent, allowing you to effectively manage your blood sugar levels and achieve your weight loss goals.
Does Semaglutide Require Refrigeration?
Yes, semaglutide requires refrigeration before being used for the first time. It should be stored in the refrigerator at a temperature between 36°F and 46°F (2°C and 8°C) to maintain its stability.
However, depending on the brand and specific instructions, certain semaglutide products can be kept at room temperature for a limited time after the first use.
Rybelsus: Semaglutide in Oral Tablet Form
Store Rybelsus at room temperature, between 68°F and 77°F (20°C to 25°C), in a dry location to protect it from moisture.
Ozempic: Injectable Semaglutide
Before First Use: Keep the new, unused Ozempic pen refrigerated at a temperature between 36°F and 46°F (2°C to 8°C).
After First Use: Once in use, store your pen for up to 56 days either at room temperature between 59°F and 86°F (15°C to 30°C) or refrigerated between 36°F and 46°F (2°C to 8°C).
Wegovy: Injectable Semaglutide for Weight Management
According to its manufacturer, Novo Nordisk, the Wegovy pen must be kept refrigerated at 36°F to 46°F (2°C to 8°C). If necessary, and before removing the pen cap, it can be stored in its original carton for up to 28 days at temperatures between 46°F and 86°F (8°C to 30°C).
Freezing Wegovy will destroy the active ingredient (semaglutide).
Compounded Semaglutide
Compounded semaglutide from LookMeds, like branded versions, must be refrigerated when provided as a liquid solution for injection. This ensures the medication remains stable and prevents bacterial growth or degradation that can occur at room temperature.
Unopened and unused semaglutide vials should be stored between 36-46°F (2-8°C). Upon receiving your semaglutide, it’s essential to refrigerate it immediately to maintain the correct storage conditions and protect it from extreme temperatures and sunlight.
Best Practices for Storing Semaglutide
Here are some tips to ensure your semaglutide remains effective throughout its use:
1. Store in the Original Packaging
Keep the pen in its original box to protect it from light, which can degrade the medication over time.
2. Avoid Temperature Extremes
Never expose semaglutide to temperatures above 86°F (30°C) or below freezing.
3. Avoid Direct Exposure To Sunlight
Direct sunlight can degrade semaglutide, reducing its effectiveness. Always store it in its original packaging or a shaded, protective case to maintain stability.
4. Use a Refrigerator Thermometer
A small, inexpensive thermometer can help you monitor the temperature inside your fridge to ensure it stays within the recommended range.
5. Travel Smart
When traveling, use an insulated bag or cooler with ice packs to keep the medication cold. Ensure the pen doesn’t come into direct contact with the ice pack to avoid freezing.
6. Discard Expired Medication
Always check the expiration date and discard any unused pens that have been stored beyond the recommended time frame.
Why Freezing Semaglutide Is a Problem
One of the most critical storage precautions is avoiding freezing, which can permanently damage the medication and cause it to lose effectiveness.
If semaglutide has accidentally frozen, do not attempt to thaw it or use it, as its integrity cannot be guaranteed.
What If Semaglutide Isn’t Stored Correctly?
Improper storage of semaglutide can compromise its effectiveness. Signs of improperly stored semaglutide include:
- Appearance: The solution should be clear and colorless. Any cloudiness or discoloration is a sign of degradation.
- Presence of Particles: The liquid should not contain visible particles.
- Consistency: If the liquid looks cloudy or contains visible clumps, that’s a sign of degradation.
- Unexpected Loss of Effectiveness: If your symptoms worsen despite regular dosing, it could be due to compromised medication.
If you suspect that your semaglutide has been improperly stored, consult your pharmacist or healthcare provider before using it.
Frequently Asked Questions
1. Can I Use Semaglutide That Was Left Out Overnight?
- If semaglutide was left at room temperature (up to 77°F) for less than the brand-specific limit (28–56 days), it may still be safe to use. If exposed to higher temperatures or for longer durations, it should be discarded.
2. What Happens If Semaglutide Freezes?
- Freezing damages the medication permanently, making it unsafe to use.
3. How Do I Travel with Semaglutide?
- Use an insulated bag or cooler to keep the medication within the recommended temperature range. If traveling by air, avoid checking it with luggage to prevent extreme temperature exposure.
Bottom Line
Proper storage of semaglutide is essential to ensure its effectiveness in managing your health. Always refrigerate it before first use and follow the brand-specific guidelines for room-temperature storage.
Taking these precautions will help you get the most out of your semaglutide treatment, whether for managing diabetes or supporting your weight loss journey.
If you’re ready to start your semaglutide journey or need further guidance, LookMeds is here to help. Get started today for trusted advice and resources to make your health goals a reality!
